A case published in the Journal of Preventive Medicine and Public Health described a 42-year-old professional welder who performed inert gas tungsten arc welding on copper-coated materials without wearing a protective mask or using local ventilation. Immediately after finishing work, he noticed a strong metallic taste. Within a few hours, he developed headache, chills, chest discomfort, myalgia, arthralgia, feverish sensations, thirst, and general weakness.
The following day, after repeating the same copper welding task, all symptoms worsened significantly. Blood tests revealed transient neutrophilia, eosinophilia, an elevated erythrocyte sedimentation rate, and positive C-reactive protein. Both blood and urine copper levels were significantly higher than those of his wife, who had no occupational exposure. His symptoms gradually subsided only after two full weeks away from copper welding. The report confirmed that exposure to copper fumes alone can trigger classic metal fume fever, even without the presence of zinc.
A similar but more severe situation was reported in a 2022 case study published on PMC. In this report, a middle-aged welder spent several hours welding galvanized steel inside a poorly ventilated ditch. Within hours, he developed a dry cough, high fever, severe headache, dyspnea, and vomiting.
Laboratory testing showed dramatically elevated high-sensitivity C-reactive protein levels, neutrophilia, and urine zinc levels exceeding 3,500 μg/24h. Although his oxygen saturation remained at 97.9%, he required corticosteroid treatment for recovery. Antibiotics were ineffective because the condition was chemical pneumonitis caused by zinc oxide fumes, rather than a bacterial infection.
Together, these reports highlight how exposure to welding fumes—especially in poorly ventilated environments—can rapidly lead to metal fume fever or even serious lung injury.